Alternative Systemic Treatments for Vitiligo: A Review.
作者： Brandon E. Cohen , Nada Elbuluk , Euphemia W. Mu , Seth J. Orlow
DOI: 10.1007/S40257-015-0153-5
关键词: Vitamin 、 Medicine 、 Khellin 、 Ultraviolet therapy 、 Pharmacotherapy 、 Vitiligo 、 Dermatology 、 Ginkgo biloba 、 Adverse effect 、 Phytotherapy
摘要: Vitiligo is a common, acquired disorder of skin pigmentation that can significantly impact quality life. It often represents therapeutic challenge, which has resulted in interest alternative treatments such as herbal and vitamin supplements. In this review, we provide an overview the most commonly studied complementary agents, describe proposed mechanisms action, identify potential adverse effects, discuss primary evidence supporting their use. Our discussion focuses on L-phenylalanine, Polypodium leucotomos, khellin, Ginkgo biloba, vitamins minerals, including B12, C, E, folic acid, zinc used monotherapy or combination with other for management vitiligo.
springer.com
sci-hub.se 参考文章(64)
Alain Taïeb, Mauro Picardo, Vitiligo New England Journal of Medicine. ,vol. 360, pp. 160- 169 ,(2009) , 10.1056/NEJMCP0804388
M L Diaz, N J Garcia, L F Montes, J Lajous, Folic acid and vitamin B12 in vitiligo: a nutritional approach. Cutis. ,vol. 50, pp. 39- 42 ,(1992)
Noah Scheinfeld, Patrick Emanuel, A review of DNA repair and possible DNA-repair adjuvants and selected natural anti-oxidants. Dermatology Online Journal. ,vol. 13, pp. 10- ,(2007)
F R Ochsendorf, D Greiner, R Milbradt, [Vitiligo therapy with phenylalanine/UV A. Catamnestic studies after five years]. Hautarzt. ,vol. 45, pp. 460- 463 ,(1994) , 10.1007/S001050050104
José Mazuecos, Francisco Camacho, Oral and topical L-phenylalanine, clobetasol propionate, and UVA/sunlight--a new study for the treatment of vitiligo. Journal of Drugs in Dermatology. ,vol. 1, pp. 127- 131 ,(2002)
Valerie Callender, Neil Sadick, Mark Nestor, Joel L Cohen, Vivian Bucay, Heidi Waldorf, Polypodium leucotomos as an Adjunct Treatment of Pigmentary Disorders. The Journal of clinical and aesthetic dermatology. ,vol. 7, pp. 13- 17 ,(2014)
AS Karadag, E Tutal, DT Ertugrul, KO Akin, SG Bilgili, None, Serum holotranscobalamine, vitamin B12, folic acid and homocysteine levels in patients with vitiligo Clinical and Experimental Dermatology. ,vol. 37, pp. 62- 64 ,(2012) , 10.1111/J.1365-2230.2011.04142.X
W. L. Ryan, M. J. Carver, INHIBITION OF ANTIBODY SYNTHESIS BY L-PHENYLALANINE. Science. ,vol. 143, pp. 479- 480 ,(1964) , 10.1126/SCIENCE.143.3605.479
M J Olsson, L Juhlin, Improvement of vitiligo after oral treatment with vitamin B12 and folic acid and the importance of sun exposure. Acta Dermato-venereologica. ,vol. 77, pp. 460- 462 ,(1997) , 10.2340/000155555577460462
Peter Wolf, Angelika Hofer, Helmut Kerl, Long-term results in the treatment of vitiligo with oral khellin plus UVA European Journal of Dermatology. ,vol. 11, pp. 225- 229 ,(2001)