On the relationship between glycerophosphoglycolipids and lipoteichoic acids in Gram-positive bacteria. II. Structures of glycerophosphoglycolipids.

作者: Werner Fischer , Raili A. Laine , Masuo Nakano

DOI: 10.1016/0005-2760(78)90019-X

关键词: StereochemistryGram-positive bacteriaBacillus subtilisStreptococcusGlycerolLactobacillus plantarumBiochemistryBacillus licheniformisBiologyBacteriaLactobacillus casei

摘要: Abstract 1. Eight glycerophosphoglycolipids were isolated from six Gram-positive bacteria. Besides sn-glycero-1-phospho-β-gentiobiosyldiacylglycerol (i) and sn-glycero-1-phospho-α-kojibiosyldiacylglycerol (ii), three novel structures have been established: 1,2-di-O-acyl-3-O-[6-(sn-glycero-1-phospho)-α-D-glucopyranosyl-(1 → 2)-(6-O-acyl-α-D-glucopyranosyl)]glycerol (iii), 1,2-di-O-acyl-3-O-[6-(sn-glycero-1-phospho)-β-D-glucopyranosyl- 6)-α-D-galactopyranosyl-(1 2)-α-D-glucopyranosyl]glycerol (iv),and 1,2-di-O-acyl-3-O-[6-(sn-glycero-1-phospho)-β-D-glucopyranosyl-(1 2)-(6-O-acyl-α-D-glucopyranosyl)]iglycerol (v). 2. Compound i was Bacillus licheniformis, subtilis Staphylococcus aureus, compound ii a group B Streptococcus, compounds iii Streptococcus lactis, iv v Lactobacillus casei. plantarum contained besides glycerophosphate derivative of 1,2-di-O-acyl-3-O-[α-D-galactopyranosyl (1 2)-α-D-glucopyranosyl]glycerol. 3. Identical structural features the described corresponding lipoteichoic acids are discussed.

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