Striatal structure and function in mood disorders: a comprehensive review
作者： William R Marchand , Deborah Yurgelun-Todd
DOI: 10.1111/J.1399-5618.2010.00874.X
关键词: Mood disorders 、 Psychology 、 Basal ganglia 、 Bipolar disorder 、 Additional research 、 Critical appraisal 、 Neuroscience 、 Structure and function 、 Functional imaging
摘要: Marchand WR, Yurgelun-Todd D. Striatal structure and function in mood disorders: a comprehensive review. Bipolar Disord 2010: 12: 764–785. © 2010 The Authors. Journal compilation John Wiley & Sons A/S. Objectives: A large diverse literature has implicated abnormalities of striatal both unipolar bipolar disorder. Recent functional imaging studies have greatly expanded this body research. aim review is to provide critical appraisal the relevant literature. Methods: total 331 articles were reviewed develop an integrated overview disorders. Results: There compelling evidence from multiple that striatum greater corticostriatal circuitry exist at least some forms affective illness. does not yet data determine whether these aberrations represent primary pathology or they contribute directly symptom expression. Finally, there considerable disorder may be associated with hyperactivity suggestion illness hypoactivation. Conclusions: Additional research investigating disorders will development models neurobiology conditions.
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