Peptides, pharmaceutical compositions comprising same and uses thereof

摘要: Use of an isolated peptide comprising amino acid sequence being no more than 25 acids in length, the at least one aspartate or a homolog thereof, having Insulin-Degrading Enzyme (IDE) inhibitory activity, for manufacture medicament identified treating disease selected from group consisting diabetes, obesity, hyperglycemia, retinal damage, renal failure, nerve microvascular damage and varicella-zoster virus (VZV) infection is disclosed.