Carboxamide modified polyamine chelators and radioactive complexes and conjugation

作者: A. Dean Sherry , William J. Kruper , William A. Fordyce

DOI:

关键词: StereochemistryMetal ions in aqueous solutionChemistryPolyamineCovalent bondCarboxamide

摘要: A group of functionalized polyaminocarboxamide modified chelators that form complexes with rare earth-type metal ions are disclosed. The complexes, covalently attached to an antibody or fragment, can be used for therapeutic and/or diagnostic purposes.

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