Efficient metathesis route to the B-ring of eleutherobin and other medium-sized cyclic ethers
作者： Krishna P. Kaliappan , Nirmal Kumar
DOI: 10.1016/J.TET.2005.05.045
关键词: Grubbs' catalyst 、 Bicyclic molecule 、 Chemistry 、 Ring-closing metathesis 、 Stereochemistry 、 Eleutherobin 、 Ring (chemistry) 、 Metathesis 、 Combinatorial chemistry
摘要: A short and efficient RCM route is reported for the synthesis of B-ring eleutherobin other medium-sized cyclic ethers from readily available 1,2,5,6-diisopropylidene-D-glucose. This strategy successfully extended to a few bicyclic ethers, which may find applications in novel nucleosides.
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