Anti-CS1 humanized monoclonal antibody HuLuc63 inhibits myeloma cell adhesion and induces antibody-dependent cellular cytotoxicity in the bone marrow milieu
作者： Yu-Tzu Tai , Myles Dillon , Weihua Song , Merav Leiba , Xian-Feng Li
DOI: 10.1182/BLOOD-2007-08-107292
关键词: Monoclonal antibody 、 Stromal cell 、 SLAMF7 、 Cell adhesion 、 Antibody-dependent cell-mediated cytotoxicity 、 Molecular biology 、 Bortezomib 、 Bone marrow 、 Biology 、 Antigen
摘要: Currently, no approved monoclonal antibody (mAb) therapies exist for human multiple myeloma (MM). Here we characterized cell surface CS1 as a novel MM antigen and further …
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