Studies with mustards. I. Ion-exchange chromatography of reaction mixtures of purines and pyrimidines with nitrogen mustard

作者: Glynn P. Wheeler , Jeanenne S. Morrow , Howard E. Skipper

DOI: 10.1016/0003-9861(55)90184-3

关键词: Purine metabolismNitrogen mustardIon chromatographyUracilGuanineChemistryOrganic chemistryThymineBiophysicsBiochemistryMolecular biology

摘要: Abstract The data presented in this report indicate that nitrogen mustard can react vitro with adenine, guanine, thymine, and uracil, isolable products are formed. It has been shown ion-exchange chromatography resolved, at least to a certain extent, reaction mixtures of these bases HN2 into the components.

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