Pathologic examination of the sentinel lymph node

摘要: The technique of sentinel lymph node biopsy has permitted accurate identification by surgeons and nuclear medicine physicians the first to receive direct drainage from an area tumor. This selective dissection draining had added benefit dramatically reducing number nodes pathologist must examine in search for metastatic turn made feasible routine examination multiple levels submitted tissue use immunohistochemical stains, both which been proven, even pre-sentinel era, improve detection occult metastases, impart a poor prognosis. While optimal method pathologic remains “a work progress”, at least three block, stains antigens such as S-100 (for melanoma) keratin proteins carcinoma) seems constitute current “standard care”. value highly sensitive methods, PCR, metastases subject active investigation.