Soluble TNF Mediates the Transition from Pulmonary Inflammation to Fibrosis
作者： Nikos Oikonomou , Vaggelis Harokopos , Jonathan Zalevsky , Christos Valavanis , Anastasia Kotanidou
DOI: 10.1371/JOURNAL.PONE.0000108
关键词: Inflammation 、 Pulmonary fibrosis 、 Receptor 、 Bleomycin 、 Idiopathic pulmonary fibrosis 、 Fibrosis 、 Wound healing 、 Medicine 、 Tumor necrosis factor alpha 、 Pathology
摘要: Background Fibrosis, the replacement of functional tissue with excessive fibrous tissue, can occur in all main tissues and organ systems, resulting various pathological disorders. Idiopathic Pulmonary Fibrosis is a prototype fibrotic disease involving abnormal wound healing response to multiple sites ongoing alveolar epithelial injury.
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