Chemical stability of cyclophosphamide, trofosfamide, and 2- and 3-dechloroethylifosfamide in aqueous solutions
作者： G.P. Kaijser , T. Aalbers , J.H. Beijnen , A. Bult , W.J.M. Underberg
DOI: 10.1177/107815529600200102
关键词: Ifosfamide 、 Aqueous solution 、 Chemical stability 、 Medicine 、 Cyclophosphamide 、 Trofosfamide 、 Kinetics 、 Chromatography 、 Degradation kinetics
摘要: The degradation kinetics of various oxazaphospho rines : trofosfamide, cyclophosphamide, and 2- 3-dechloroethylifosfamide was studied by means a high-performance liquid chromatographic method. results were compared with the ifosfamide. It appeared that pres ence site chloroethyl group influ enced chemical stability compounds.
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