On the Androgen Microenvironment of Maturing Spermatozoa

作者: T. T. TURNER , C. E. JONES , S. S. HOWARDS , L. L. EWING , B. ZEGEYE

DOI: 10.1210/ENDO-115-5-1925

关键词: EndocrinologyTestosteroneInterstitial fluidSpermInternal medicineAndrologyBiologyAndrogenSeminiferous tubule fluidEfferent ductsReabsorptionIn vivo

摘要: Adult anesthetized male rats were submitted to in vivo micropuncture of the seminiferous and epididymal tubules reproductive tract vasculature obtain fluids for analysis testosterone, 5α-dihydrotestosterone, androgenbinding protein (ABP). Androgen ABP concentrations determined by RIA. The highest testosterone (73.14 ± 5.12 ng/ml) testicular interstitial fluid. A significant downhill concentration gradient exists between fluid tubule (50.24 2.26 ng/ml); another decrease occurs rete testis (17.85 2.11 ng/ml). 5α-Dihydrotestosterone intraluminal caput epididymidal (58.73 6.48 as (33.30 2.40 μleq/μl). Intraluminal sperm also determined, from these data, reabsorption efferent ducts calculate...

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