Klebsiella pneumoniae oropharyngeal carriage in rural and urban Vietnam and the effect of alcohol consumption.

作者: Trinh Tuyet Dao , Dror Liebenthal , Toan Khanh Tran , Bich Ngoc Thi Vu , Diep Ngoc Thi Nguyen

DOI: 10.1371/JOURNAL.PONE.0091999

关键词: Risk factorCarriageCross-sectional studyPopulationYoung adultKlebsiella pneumoniaeMedicinePneumoniaEnvironmental healthSocioeconomic statusPediatrics

摘要: INTRODUCTION: Community acquired K. pneumoniae pneumonia is still common in Asia and reportedly associated with alcohol use. Oropharyngeal carriage of could potentially play a role the pathogenesis pneumonia. However, little known regarding oropharyngeal rates risk factors. This population-based cross-sectional study explores association variety demographic socioeconomic factors, as well consumption Vietnam. METHODS AND FINDINGS: 1029 subjects were selected randomly from age, sex, urban rural strata. An additional 613 adult men environment recruited analyzed separately to determine effects consumption. Demographic, socioeconomic, data was for each subject. The overall rate 14.1% (145/1029, 95% CI 12.0%-16.2%). By stepwise logistic regression, found be independently age (OR 1.03, 1.02-1.04), smoking 1.9, 1.3-2.9), living location 1.6, 1.1-2.4), level weekly 1.7, 1.04-2.8). CONCLUSION: Moderate heavy consumption, old smoking, are all an increased Vietnamese communities. Whether factor needs elucidated.

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