Impaired vestibulo-ocular reflex (VOR) in spinocerebellar ataxia type 3 (SCA3): bedside and search coil evaluation.
作者： Carlos R. Gordon , Ari Z. Zivotofsky , Avi Caspi
DOI: 10.3233/VES-140527
关键词: Audiology 、 Vestibular areflexia 、 Psychology 、 Machado–Joseph disease 、 Head impulse test 、 Reflex 、 Eye movement 、 Vestibular system 、 Vestibulo–ocular reflex 、 Spinocerebellar ataxia
摘要: Vestibulo-Ocular Reflex (VOR) abnormalities in cerebellar ataxias are a matter of renewed interest. We have previously reported vestibular areflexia group Yemenite-Jews with Spinocerebellar Ataxia Type 3 (SCA3) who had clear bilateral pathological horizontal Head Impulse Test (HIT). The objective this study was to evaluate the VOR ten SCA3 patients variable bedside HIT responses by recording their eye movements using magnetic search coils and correlate these results clinical genetic data. Eight out abnormal detected both examination laboratory tests. Results testing were significantly correlated gain recorded coils. No significant correlations found between other or Our confirms presence defective corroborates useful as reliable test for diagnosis deficits.
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