Expression of an active LKB1 complex in cardiac myocytes results in decreased protein synthesis associated with phenylephrine-induced hypertrophy

作者: Anna A. Noga , Carrie-Lynn M. Soltys , Amy J. Barr , Suzanne Kovacic , Gary D. Lopaschuk

DOI: 10.1152/AJPHEART.01133.2006

关键词: AMPKMyocyteInternal medicineEndocrinologyMuscle hypertrophyProtein kinase ABiologyPhenylephrineRegulatorCardiac myocyteAdenosine kinase

摘要: AMP-activated protein kinase (AMPK) is a major metabolic regulator in the cardiac myocyte. Recently, LKB1 was identified as that regulates AMPK. Using immunoblot analysis, we confirmed hig...

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