CD40 deficiency in mice exacerbates obesity-induced adipose tissue inflammation, hepatic steatosis, and insulin resistance.
作者： Chang-An Guo , Sophia Kogan , Shinya U. Amano , Mengxi Wang , Sezin Dagdeviren
DOI: 10.1152/AJPENDO.00514.2012
关键词: Inflammation 、 Adipose tissue 、 Adipose tissue macrophages 、 Internal medicine 、 White adipose tissue 、 Insulin resistance 、 Biology 、 Fatty liver 、 Type 2 diabetes 、 Endocrinology 、 Steatosis 、 Immunology
摘要: The pathophysiology of obesity and type 2 diabetes in rodents humans is characterized by low-grade inflammation adipose tissue liver. CD40 receptor its ligand CD40L initiate immu...
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