Protein tyrosine phosphatase 1B inhibitors from natural sources.
作者： Bing Tian Zhao , Duc Hung Nguyen , Duc Dat Le , Jae Sue Choi , Byung Sun Min
DOI: 10.1007/S12272-017-0997-8
关键词: Enzyme 、 Research studies 、 Biology 、 Drug discovery 、 Research community 、 Protein Tyrosine Phosphatase 1B 、 Pharmacology toxicology 、 Computational biology
摘要: Since PTP1B enzyme was discovered in 1988, it has captured the research community's attention. This landmark discovery stimulated numerous studies on a variety of human diseases, including cancer, inflammation, and diabetes. Tremendous progress been made finding inhibitors exploring regulatory mechanisms. review investigates for natural inhibitors, focuses common characteristics structures structure-activity relationships. To facilitate understanding, all compounds are here divided into five different classes (fatty acids, phenolics, terpenoids, steroids, alkaloids), according to their skeletons. These scaffold could serve as theoretical basis new concept drug design.
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sci-hub.se 参考文章(221)
Hyeongjin Cho, Protein Tyrosine Phosphatase 1B (PTP1B) and Obesity Vitamins & Hormones. ,vol. 91, pp. 405- 424 ,(2013) , 10.1016/B978-0-12-407766-9.00017-1
J S Choi, H A Jung, M N Islam, S S Chowdhury, In vitro antidiabetic potential of the fruits of Crataegus pinnatifida. Research in Pharmaceutical Sciences. ,vol. 9, pp. 11- 22 ,(2014)
Jae Sue Choi, Md. Yousof Ali, Hyun Ah Jung, Sang Ho Oh, Ran Joo Choi, Eon Ji Kim, Protein tyrosine phosphatase 1B inhibitory activity of alkaloids from Rhizoma Coptidis and their molecular docking studies Journal of Ethnopharmacology. ,vol. 171, pp. 28- 36 ,(2015) , 10.1016/J.JEP.2015.05.020
Jong-Soo Lee, Delfly B Abdjul, Hiroyuki Yamazaki, Ohgi Takahashi, Ryota Kirikoshi, Kazuyo Ukai, Michio Namikoshi, None, Strongylophorines, new protein tyrosine phosphatase 1B inhibitors, from the marine sponge Strongylophora strongilata collected at Iriomote Island Bioorganic & Medicinal Chemistry Letters. ,vol. 25, pp. 3900- 3902 ,(2015) , 10.1016/J.BMCL.2015.07.039
Gong-Min Lin, Yu-Han Chen, Pei-Ling Yen, Shang-Tzen Chang, None, Antihyperglycemic and antioxidant activities of twig extract from Cinnamomum osmophloeum. Journal of Traditional and Complementary Medicine. ,vol. 6, pp. 281- 288 ,(2016) , 10.1016/J.JTCME.2015.08.005
Xu Liu, Xiaoming Li, Lixin Gao, Chuanming Cui, Chunshun Li, Jia Li, Bingui Wang, Extraction and PTP1B inhibitory activity of bromophenols from the marine red alga Symphyocladia latiuscula Chinese Journal of Oceanology and Limnology. ,vol. 29, pp. 686- 690 ,(2011) , 10.1007/S00343-011-0136-1
Jing Sun, Yongsen Wang, Xueqi Fu, Yingli Chen, Deli Wang, Wannan Li, Shu Xing, Guodong Li, Magnolia officinalis Extract Contains Potent Inhibitors against PTP1B and Attenuates Hyperglycemia in db/db Mice. BioMed Research International. ,vol. 2015, pp. 139451- 139451 ,(2015) , 10.1155/2015/139451
N K Tonks, C D Diltz, E H Fischer, Purification of the major protein-tyrosine-phosphatases of human placenta. Journal of Biological Chemistry. ,vol. 263, pp. 6722- 6730 ,(1988) , 10.1016/S0021-9258(18)68702-2
Tran Hong Quang, Nguyen Thi Thanh Ngan, Chi-Su Yoon, Kwang-Ho Cho, Dae Gill Kang, Ho Sub Lee, Youn-Chul Kim, Hyuncheol Oh, None, Protein Tyrosine Phosphatase 1B Inhibitors from the Roots of Cudrania tricuspidata Molecules. ,vol. 20, pp. 11173- 11183 ,(2015) , 10.3390/MOLECULES200611173
Barry J. Goldstein, Pei-Ming Li, Wendi Ding, Faiyaz Ahmad, Wei-Ren Zhang, Regulation of insulin action by protein tyrosine phosphatases. Vitamins and Hormones Series. ,vol. 54, pp. 67- 96 ,(1998) , 10.1016/S0083-6729(08)60922-X