Severe hepatitis C infection in a renal transplant recipient following hepatitis C genotype mismatch transplant.
作者： Thomas Schussler , Catherine Staffeld-Coit , James Eason , Satheesh Nair
DOI: 10.1111/J.1600-6143.2004.00504.X
关键词: Tacrolimus 、 Gastroenterology 、 Internal medicine 、 Transaminase 、 Hepatitis C 、 Hepatitis 、 Inflammation 、 Medicine 、 Genotype 、 Immunosuppression 、 Kidney transplantation
摘要: We report a case of 32-year-old female with histologically and clinically inactive chronic hepatic C infection, who received cadaveric renal transplant from hepatitis C-positive donor different genotype. The genotype mismatch (genotype 1 to 2) change tacrolimus-based immunosuppression resulted in severe infection characterized by 10-fold increase transaminase levels grade 3 inflammation histologically. Our highlights the risk genotype-mismatch transplants solid organ transplantation.
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