Chromatin remodeling in DNA replication

作者: Karina B. Falbo , Xuetong Shen

DOI: 10.1002/JCB.20752

关键词: Cell biologyScaffold/matrix attachment regionMi-2/NuRD complexBiologyGeneticsChIA-PETATP-dependent chromatin remodelingEukaryotic DNA replicationChromatin remodelingOrigin recognition complexChromatin

摘要: Chromatin remodeling complexes have evolved to solve a very basic problem for eukaryotic cells accommodation of the genome fit dimensions nucleus without loss access DNA molecule. In nucleus, is wrapped around histones form nucleosomes and other higher order compact chromatin structures. enable highly regulated sequences in context chromatin, it well known that these are involved regulation transcription. However, gene expression not only process occurs nucleus. has be replicated, recombined, repaired. this regard, notable recent discoveries linked ATP-dependent damage repair. These results raised challenging questions about possible versatility nuclear activities, particularly replication, since number studies suggested connection between essential cellular remodeling. events regulating replication been extensively investigated. The aim prospect summarize implicate address potential roles at various stages replication.

参考文章(23)
Raymond A. Poot, Ludmila Bozhenok, Debbie L.C. van den Berg, Søren Steffensen, Fernando Ferreira, Margaret Grimaldi, Nick Gilbert, Joao Ferreira, Patrick D. Varga-Weisz, The Williams syndrome transcription factor interacts with PCNA to target chromatin remodelling by ISWI to replication foci Nature Cell Biology. ,vol. 6, pp. 1236- 1244 ,(2004) , 10.1038/NCB1196
Jing Zhou, Charles M Chau, Zhong Deng, Ramin Shiekhattar, Mark-Peter Spindler, Aloys Schepers, Paul M Lieberman, Cell cycle regulation of chromatin at an origin of DNA replication The EMBO Journal. ,vol. 24, pp. 1406- 1417 ,(2005) , 10.1038/SJ.EMBOJ.7600609
Mónica Segurado, Alberto de Luis, Francisco Antequera, Genome‐wide distribution of DNA replication origins at A+T‐rich islands in Schizosaccharomyces pombe EMBO Reports. ,vol. 4, pp. 1048- 1053 ,(2003) , 10.1038/SJ.EMBOR.7400008
Nadine Collins, Raymond A. Poot, Iwao Kukimoto, Custodia García-Jiménez, Graham Dellaire, Patrick D. Varga-Weisz, An ACF1-ISWI chromatin-remodeling complex is required for DNA replication through heterochromatin. Nature Genetics. ,vol. 32, pp. 627- 632 ,(2002) , 10.1038/NG1046
David Y Takeda, Anindya Dutta, DNA replication and progression through S phase Oncogene. ,vol. 24, pp. 2827- 2843 ,(2005) , 10.1038/SJ.ONC.1208616
Giovanni Maga, Ulrich Hubscher, Proliferating cell nuclear antigen (PCNA): a dancer with many partners Journal of Cell Science. ,vol. 116, pp. 3051- 3060 ,(2003) , 10.1242/JCS.00653
Hinrich Boeger, Joachim Griesenbeck, J.Seth Strattan, Roger D. Kornberg, Nucleosomes unfold completely at a transcriptionally active promoter. Molecular Cell. ,vol. 11, pp. 1587- 1598 ,(2003) , 10.1016/S1097-2765(03)00231-4
Gaku Mizuguchi, Xuetong Shen, Joe Landry, Wei-Hua Wu, Subhojit Sen, Carl Wu, ATP-Driven Exchange of Histone H2AZ Variant Catalyzed by SWR1 Chromatin Remodeling Complex Science. ,vol. 303, pp. 343- 348 ,(2004) , 10.1126/SCIENCE.1090701
Haico van Attikum, Olivier Fritsch, Barbara Hohn, Susan M. Gasser, Recruitment of the INO80 Complex by H2A Phosphorylation Links ATP-Dependent Chromatin Remodeling with DNA Double-Strand Break Repair Cell. ,vol. 119, pp. 777- 788 ,(2004) , 10.1016/J.CELL.2004.11.033
Anthony T. Annunziato, Split decision: what happens to nucleosomes during DNA replication? Journal of Biological Chemistry. ,vol. 280, pp. 12065- 12068 ,(2005) , 10.1074/JBC.R400039200