Cyclic Analogues of Horseshoe Crab Peptide Tachyplesin I with Anticancer and Cell Penetrating Properties

作者: Felicitas Vernen , David J. Craik , Nicole Lawrence , Sónia Troeira Henriques

DOI: 10.1021/ACSCHEMBIO.9B00782

关键词: Horseshoe crabCytotoxic T cellPeptideCellTachypleus tridentatusPeptide sequenceBiophysicsCell-penetrating peptideCell cultureChemistry

摘要: … Tachyplesin I (TI) is a cationic HDP isolated from hemocytes … Cyclic TI (cTI) analogues are backbone cyclized between the … insert into lipid membranes that mimic the negatively charged …

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