Developing a new chemosensor targeting zinc ion based on two types of quinoline platform.

作者: Ahran Kim , Hangyul Lee , Dongju Yun , Ukhyun Jung , Ki-Tae Kim

DOI: 10.1016/J.SAA.2020.118652

关键词: ChemistryNuclear chemistryProton NMRZincDetection limitQuinolineTitrationMass spectrometryFluorescenceAcetamide

摘要: Abstract A chemosensor DQ (2-(2-(quinolin-2-yl)hydrazinyl)-N-(quinolin-8-yl)acetamide), based on two quinoline moieties, has been synthesized. could detect zinc ion through fluorescence turn-on in aqueous media. Limit of detection was calculated as 0.07 μM, far lower than the standard WHO for ion. The practicality demonstrated via successful results reusability with EDTA, easy test strip, and precise quantification real water samples. Additionally, sensor be applied to bioimaging zebrafish. Sensing process by studied UV–Vis spectroscopy, 1H NMR titration, ESI-mass spectrometry.

参考文章(56)
Vinod Kumar Gupta, Naveen Mergu, Ashok Kumar Singh, Rhodamine-derived highly sensitive and selective colorimetric and off–on optical chemosensors for Cr3+ Sensors and Actuators B-chemical. ,vol. 220, pp. 420- 432 ,(2015) , 10.1016/J.SNB.2015.05.075
Gyeong Jin Park, Jae Jun Lee, Ga Rim You, LeTuyen Nguyen, Insup Noh, Cheal Kim, A dual chemosensor for Zn2+ and Co2+ in aqueous media and living cells: Experimental and theoretical studies Sensors and Actuators B-chemical. ,vol. 223, pp. 509- 519 ,(2016) , 10.1016/J.SNB.2015.09.129
Elizabeth M. Nolan, Jacek Jaworski, Ken-Ichi Okamoto, Yasunori Hayashi, Morgan Sheng, Stephen J. Lippard, QZ1 and QZ2:  Rapid, Reversible Quinoline-Derivatized Fluoresceins for Sensing Biological Zn(II) Journal of the American Chemical Society. ,vol. 127, pp. 16812- 16823 ,(2005) , 10.1021/JA052184T
Xiuli Fu, Lingxin Chen, Jinhua Li, Meng Lin, Huiyan You, Wenhai Wang, Label-free colorimetric sensor for ultrasensitive detection of heparin based on color quenching of gold nanorods by graphene oxide Biosensors and Bioelectronics. ,vol. 34, pp. 227- 231 ,(2012) , 10.1016/J.BIOS.2012.02.008
Nagarjun Narayanaswamy, T. Govindaraju, Aldazine-based colorimetric sensors for Cu2+ and Fe3+ Sensors and Actuators B-chemical. ,vol. 161, pp. 304- 310 ,(2012) , 10.1016/J.SNB.2011.10.036
Jinhua Li, Zhong Zhang, Shoufang Xu, Lingxin Chen, Na Zhou, Hua Xiong, Hailong Peng, Label-free colorimetric detection of trace cholesterol based on molecularly imprinted photonic hydrogels Journal of Materials Chemistry. ,vol. 21, pp. 19267- 19274 ,(2011) , 10.1039/C1JM14230E
Lijun Tang, Xin Dai, Xin Wen, Di Wu, Qiang Zhang, A rhodamine–benzothiazole conjugated sensor for colorimetric, ratiometric and sequential recognition of copper(II) and sulfide in aqueous media Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. ,vol. 139, pp. 329- 334 ,(2015) , 10.1016/J.SAA.2014.12.055
He-yang Li, Shuang Gao, Zhen Xi, A colorimetric and “turn-on” fluorescent chemosensor for Zn(II) based on coumarin Shiff-base derivative Inorganic Chemistry Communications. ,vol. 12, pp. 300- 303 ,(2009) , 10.1016/J.INOCHE.2009.01.013
Lijun Tang, Pei Zhou, Zhenlong Huang, Jia Zhao, Mingjun Cai, New Application of 2-(4-N-Phenyl-3-thiosemicarbazone)-8-hydroxyquinoline as a Sensor for Relay Recognition of Cu 2+ and Sulfide in Aqueous Solution Bulletin of The Korean Chemical Society. ,vol. 34, pp. 2905- 2908 ,(2013) , 10.5012/BKCS.2013.34.10.2905
Yu Liu, Ning Zhang, Yong Chen, Li-Hua Wang, Fluorescence Sensing and Binding Behavior of Aminobenzenesulfonamidoquinolino-β-cyclodextrin to Zn2+ Organic Letters. ,vol. 9, pp. 315- 318 ,(2007) , 10.1021/OL062816W