An analysis of infectious failures in acute cholangitis.

摘要: To determine the factors responsible for therapeutic failures in acute cholangitis, a series of 127 patients was analyzed. There were 64 females and 63 males whose mean age 57.2 years. Ninetyfour (74.0%) these clinically cured with initial measures, whereas 33 (26%) failed therapy an infectious reason. No differences observed between two groups regard to gender. However, more group that had malignant cause their bile duct obstruction (72.7% vs. 42.6%, p < 0.01) pretreatment positive blood culture (45.5% 13.8%, 0.01). Patients who higher total bilirubin level (9.7 mg/dl 5.5 mg/dl, 0.005) them greater than 2.2 (97% 69.9%, 0.001). Also, cultures initially (93.9% 76.6%, 0.05) organisms isolated per (3.88 2.86, 0.03) failed. In addition, or (33% 8.3%, 0.02). whom Candida, any panresistant organism also tended fail. Multivariant analysis showed malignancy, bacteremia, ≥ 2 best predictors treatment failure serum being variable increases patient's log-odds ratio greatest. conclusion, cholangitis have increased chance fail can be identified, altered accordingly.