Chemical synthesis of a core 2 branched pentasaccharide containing a carboxylate group
作者： Jie Xia , James L. Alderfer , Khushi L. Matta
DOI: 10.1016/S0960-894X(00)00497-2
关键词: Regioselectivity 、 Molecule 、 Acceptor 、 Galactoside 、 Stereochemistry 、 Carboxylate 、 Carboxylic acid 、 Chemical synthesis 、 Carbohydrate conformation 、 Chemistry
摘要: Design and synthesis of a carboxylate-containing pentasaccahride 1 with the Galbeta(1-4) (Fucalpha1-3)GlcNAcbeta(1-6)[3-[1-carboxymethyl]-Galbeta+ ++(1-3)]GalNAcalpha-OMe sequence, which is obtained through regioselective coupling 6-OH novel acceptor 9 Lewis(x) donor 10 catalyzed by NIS-TfOH are described.
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