作者: Guanqiao Jin , Pohlee Cheah , Jing Qu , Lijuan Liu , Yongfeng Zhao
DOI: 10.3390/JNT1010004
关键词: Skin cancer 、 Applications of nanotechnology 、 Nanomaterials 、 Nanotechnology 、 Clinical trial 、 Drug 、 Melanoma 、 Molecular imaging 、 Drug delivery 、 Medicine
摘要: Melanoma is an aggressive form of skin cancer with a very high mortality rate. Early diagnosis the disease, utilization more potent pharmacological agents, and effective drug delivery systems are essential to achieve optimal treatment plan. The applications nanotechnology improve therapeutic efficacy early for melanoma have received great interest among researchers clinicians. In this review, we summarize recent progress utilizing various nanomaterials theranostics melanoma. key importance using reduce side effects, ensuring safe implementation in clinical use. As opposed conventional vitro diagnostic methods, vivo medical imaging technologies advantages being type non-invasive, real-time monitoring. Several common nanoparticles, including ultrasmall superparamagnetic iron oxide silica carbon-based been applied deliver chemotherapeutic agents application molecular (MRI, PET, US, OI, etc.) plays important role targeting melanoma, by monitoring distribution site probe body real-time. Hence, it worthwhile anticipate approval these US Food Drug Administration trials.