作者: Norman E Sammons Jr , Wei Yuan , Mario R Eden , Burak Aksoy , Harry T Cullinan
DOI: 10.1016/S1570-7946(08)80186-1
关键词: Global optimization 、 Biochemical engineering 、 Engineering optimization 、 Engineering 、 Production (economics) 、 Supply chain 、 Systems engineering 、 Process (engineering) 、 Process modeling 、 Multi-objective optimization 、 Process optimization
摘要: Abstract The integrated biorefinery has the opportunity to provide an independent and sustainable alternative for production of bulk fine chemicals. Because shift towards producing energy with minimal environmental impact, there is a need methodology capable evaluating processes in order identify optimal set products pathways. complexity product allocation problem such processing facilities demands process systems engineering approach utilizing integration mathematical optimization techniques ensure targeted serve as interface between simulation work experimental efforts. objective this assist, bioprocessing industries profitability different possible routes portfolios while maximizing stakeholder value through global supply chain. To meet these ends, based framework been developed, which enables inclusion measures other technoeconomic metrics along insights obtained from well modeling studies. A case study included highlights robustness its utility decision making.