作者: M. A. Rocca , M. Cercignani , G. Iannucci , G. Comi , M. Filippi
DOI: 10.1212/WNL.55.6.882
关键词: Multiple sclerosis 、 Lesion formation 、 Pathology 、 Nuclear magnetic resonance 、 Diffusion MRI 、 White matter 、 Medicine
摘要: Article abstract To elucidate the dynamics and nature of normal-appearing white matter (NAWM) changes preceding new lesion formation in MS, authors obtained weekly diffusion-weighted images for 12 weeks from 6 patients. NAWM areas subsequently involved by enhancement had a significant increase mean diffusivity values starting before appearance ( p ranging between