作者: Robert H. Gundel , Craig D. Wegner , L. Gordon Letts
DOI: 10.1007/978-1-4613-9266-8_25
关键词: Airway inflammation 、 Immunology 、 Cell adhesion molecule 、 Glycoprotein 、 Vascular endothelium 、 Intercellular adhesion molecule 、 Cell adhesion 、 Pathogenesis 、 Respiratory epithelium 、 Medicine
摘要: The role of pro-inflammatory cells and inflammatory mediators in the pathogenesis asthma has become a subject profound investigation. process involves highly complex series events occurring at both tissue cellular levels response to diverse number stimuli. Of particular interest recent years been up-regulation enhanced expression adhesion glycoproteins on vascular endothelium circulating leukocytes that lead leukocyte margination, activation, subsequent migration out vessels into tissue.