The Role of Cellular Adhesion Molecules in Acute and Chronic Airway Inflammation

作者: Robert H. Gundel , Craig D. Wegner , L. Gordon Letts

DOI: 10.1007/978-1-4613-9266-8_25

关键词: Airway inflammationImmunologyCell adhesion moleculeGlycoproteinVascular endotheliumIntercellular adhesion moleculeCell adhesionPathogenesisRespiratory epitheliumMedicine

摘要: The role of pro-inflammatory cells and inflammatory mediators in the pathogenesis asthma has become a subject profound investigation. process involves highly complex series events occurring at both tissue cellular levels response to diverse number stimuli. Of particular interest recent years been up-regulation enhanced expression adhesion glycoproteins on vascular endothelium circulating leukocytes that lead leukocyte margination, activation, subsequent migration out vessels into tissue.

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