Acoustic perfusion devices

作者: Bart Lipkens , Erik Miller , Benjamin Ross-Johnsrud , Walter M Presz Jr , Kedar Chitale

DOI:

关键词: Tangential flowAcousticsTransducerCoolantSignalPiezoelectricityUltrasonic sensorStanding waveMaterials scienceInlet

摘要: Methods are disclosed for separating beads and cells from a host fluid. The method includes flowing mixture containing the fluid, beads, through an acoustophoretic device having ultrasonic transducer including piezoelectric material driven by drive signal to create multi-dimensional acoustic standing wave. A is sent at least one recirculating fluid stream tangential flow path located substantially wave separated therefrom interface region. portion of pass wave, held back in Also coolant inlet adapted permit ingress cooling into transducer.

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