Protein intake and renal function in older patients.

摘要: Purpose of review Chronic kidney disease (CKD) is highly prevalent in elderly patients. There growing recognition the importance attention to dietary protein intake (DPI) this population given their predisposition age-related changes function and coexisting comorbidities (i.e., hypertension). We reviewed impact DPI on health survival role management older CKD Recent findings While parameters including glomerular filtration rate (GFR) renal plasma flow are slightly lower patients irrespective status, kidneys' ability compensate for increased by augmentation GFR preserved until 80 years age or less. However, long-term consumption high individuals and/or with may contribute deterioration over time. Prescription a plant-dominant low-protein diet 0.6-0.8 g/kg/day more than 50% from plant sources very low diets less 0.45 supplemented essential amino acids keto-analogues be effective preserving younger counterparts, while also monitoring development protein-energy wasting (PEW). Summary Using tailored precision nutrition approaches prescribing that maintains adequate energy nitrogen balance ameliorate decline preventing PEW CKD.