Levonorgestrel-only dosing strategies for emergency contraception.

摘要: The United States Food and Drug Administration-approved progestin-only dosing strategy for emergency contraception is levonorgestrel 0.75 mg taken as soon possible within 72 hours of unprotected intercourse, with a second 0.75-mg dose 12 later. However, different strategies have been studied promoted by various organizations. American College Obstetricians Gynecologists recommends single 1.5 one option. As another option, they recommend two doses may be effective when 12-24 apart. We performed search MEDLINE International Pharmaceutical Abstracts from 1967-2006 to evaluate describe the existing pharmacokinetic patient outcome data regarding administration 1.5-mg or 24 Additional studies were identified bibliographies selected literature. Several pertinent articles identified. All demonstrated that effectively prevented pregnancy. In addition, evidence supports safety efficacy contraception. Furthermore, are administered, can confidently after first without compromising efficacy. Understanding critical clinicians, especially pharmacists, who interactive roles in dispensing