The ovarian response as a predictor for successful in vitro fertilization treatment after the age of 40 years

作者: Jan Roest , Arne M. van Heusden , Harold Mous , Gerard H. Zeilmaker , Arie Verhoeff

DOI: 10.1016/S0015-0282(16)58691-9

关键词: PregnancyControlled ovarian hyperstimulationObstetricsPregnancy rateRetrospective cohort studyGynecologyMedicineOvulationLogistic regressionIncidence (epidemiology)In vitro fertilisation

摘要: Objective To determine whether age or response to controlled ovarian hyperstimulation (COH) is a better predictor of IVF outcome in women≥40years. Design Retrospective analysis. Setting A transport program. Patient(s) For patients undergoing treatment the correlation between and COH was analyzed using data 2,588 consecutive cycles. Intervention(s) None. Main Outcome Measure(s) Pregnancy. Result(s) The incidence poor rises significantly with increasing age. Analysis all cycles showed significant decrease clinical ongoing pregnancy rate for good no statistically differences these parameters women≥40years those younger. logistic regression analysis on that contributes more prediction than Conclusion(s) Patients aged≥40years have prognosis treatment. limit acceptance should not be set at 40years. Instead, can used predict candidates likely successful outcome.

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