Optical characterization of acceleration-induced strain fields in inhomogeneous brain slices.

作者: C. Lauret , M. Hrapko , J.A.W. van Dommelen , G.W.M. Peters , J.S.H.M. Wismans

DOI: 10.1016/J.MEDENGPHY.2008.05.004

关键词: Nuclear magnetic resonancevon Mises yield criterionDigital image correlationPhysicsWhite matterPlanarRotation around a fixed axisSlice preparationDisplacement fieldBiomedical engineeringAcceleration

摘要: Abstract The aim of this study was to measure high-resolution strain fields in planar sections brain tissue during translational acceleration obtain validation data for numerical simulations. Slices were made from fresh, porcine tissue, and contained both grey white matter as well the complex folding structure cortex. slices immersed artificial cerebrospinal fluid (aCSF) encapsulated a rigid cavity representing actual shape skull. sustained an about 900m/s 2 velocity 4m/s followed by deceleration more than 2000m/s . During experiment, images taken using high-speed video camera Von Mises strains calculated digital image correlation technique. sampleholder determined same A rotational motion slice relative observed, which may have been caused thicker posterior part slice. Local variations displacement field found, related sulci composition Furthermore, higher seen areas around sulci.

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