A severe outbreak of haemorrhagic colitis and haemolytic uraemic syndrome associated with Escherichia coli O157:H7 in Japan.
作者： Shunji Akashi , Kohsuke Joh , Takeshi Mori , Atsutoshi Tsuji , Hiroshi Ito
DOI: 10.1007/BF02190685
关键词: Hemolytic anemia 、 Immunology 、 El Niño 、 Gastroenterology 、 Medicine 、 Abdominal pain 、 Internal medicine 、 Outbreak 、 Disease 、 Diarrhea 、 Colitis 、 Asymptomatic
摘要: In 1990, an outbreak ofEscherichia coli 0157: H7 infection occurred in 174 children a nursery school Saitama, Japan. The organism was isolated from tap water supplied the well school. Clinical manifestations varied asymptomatic to non-bloody diarrhoea, haemorrhagic colitis, haemolytic uraemic syndrome (HUS) and death. Among culture-confirmed 42 cases ofE. H7, 7 were asymptomatic, 21 had only 14 developed HUS. Bloody diarrhoea with abdominal pain following initial frequent appeared be associated subsequent patients HUS, both leucocyte count lactate dehydrogenase activity continued increase early phase of disease, on day 3 illness attained markedly higher levels than without These two parameters seemed important as predictors development
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