Simple Linear Model of Tumor Growth in a Changing Environment

摘要: In an environment that is neither static nor in equilibrium, but dynamic and changing, the kinetics of reactions cause growth a tumor, which depend on state evolving environment, cannot be parametrized terms constant rates. We propose simple model for describing untreated tumor such environments, characterized by minimal number parameters generalizable to include effects various types therapies. simplest version we consider here, it consists linear equation with time-dependent rate, interpret as coupling system environment. A complete solution given integral rate. The essential features general are illustrated few examples, comparison made models have been proposed describe recent data.