Significance of Serum Pepsinogens as a Biomarker for Gastric Cancer and Atrophic Gastritis Screening: A Systematic Review and Meta-Analysis
作者： Ya-kai Huang , Jian-chun Yu , Wei-ming Kang , Zhi-qiang Ma , Xin Ye
DOI: 10.1371/JOURNAL.PONE.0142080
关键词: Internal medicine 、 Serum pepsinogen 、 Pathology 、 Gastritis 、 Pepsin 、 Diagnostic accuracy 、 Medicine 、 Cancer 、 Meta-analysis 、 Gastroenterology 、 Atrophic gastritis 、 Biomarker (medicine) 、 General Biochemistry, Genetics and Molecular Biology 、 General Agricultural and Biological Sciences 、 General Medicine
摘要: Background Human pepsinogens are considered promising serological biomarkers for the screening of atrophic gastritis (AG) and gastric cancer (GC). However, there has been controversy in literature with respect to validity serum pepsinogen (SPG) detection GC AG. Consequently, we conducted a systematic review meta-analysis assess diagnostic accuracy SPG AG detection.
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