Food and water restriction shifts corticosterone, temperature, activity and brain amine periodicity.

作者: DOROTHY T. KRIEGER

DOI: 10.1210/ENDO-95-5-1195

关键词: EndocrinologyBiologyInternal medicineSerotoninBlood proteinsHippocampus (mythology)Hippocampal formationCorticosteronePeriod (gene)Circadian rhythmWakefulness

摘要: The circadian periodicity of plasma corticosteroid levels was determined in individual adult male and female rats, sampled every 4 hr over a 48-hr period. Access these rats to food water then restricted 9:30 AM–11:30 AM for 15-day period, the animals being kept under normal laboratory lighting conditions (lights on 8:00 AM, off PM). At end this such had 12-hr shift time peak levels. A similar alteration body temperature also seen animals. Alteration patterns running activity, with marked increase daytime activity present There reversal AM/PM ratios hippocampal norepinephrine serotonin These findings demonstrate that presence light-dark is not sufficient maintenance corticos-tero...

参考文章(1)
Erwin Bünning, The physiological clock ,(1964)