作者: Kimberley J. Hansen , Matthew S. Edwards , Timothy E. Craven , Gregory S. Cherr , Sharon A. Jackson
关键词: Cohort 、 Renal artery 、 Prospective cohort study 、 Cohort study 、 Surgery 、 Renal artery stenosis 、 Risk factor 、 Internal medicine 、 Population 、 Medicine 、 Odds ratio
摘要: Abstract Purpose: The purpose of this investigation was to estimate the population-based prevalence renovascular disease (RVD), defined as ≥60% diameter-reducing renal artery stenosis or occlusion, and define its associations with age, gender, race, other potential risk factors among participants in Cardiovascular Health Study (CHS). Methods: CHS is a multicenter, longitudinal cohort study cardiovascular factors, morbidity, mortality free-living adults more than 65 years age. As part an ancillary investigation, Forsyth County were invited undergo duplex sonography (RDS) presence absence RVD. RVD focal peak systolic velocity exceeding 1.8 m/s main occlusion when imaged lacked Doppler signal. Demographic atherosclerotic factor data gathered baseline examination. Univariable tests association performed χ 2 Student t logistic regression analysis. Multivariate examined Results: Eight hundred seventy underwent RDS. Of these examinations, 834 (96%) technically adequate RDS had mean age 77.2 ± 4.9 consisted 63% women 37% men. Participant race 76% white 23% African American. overall rate 6.8%. Among 57 patients RVD, 50 (88%) unilateral seven (12%) bilateral disease. Seven cases seen including one case contralateral stenosis. ages without 78.7 5.7 77.1 ( P = .018). present 5.5% 9.1% men .053). 6.9% 6.7% American .933). analysis revealed increasing participant .028; odds ratio, 1.34; 95% CI, 1.03, 1.73), high-density lipoprotein cholesterol levels less 40 mg/dL .003; 2.63; 1.40, 4.93), blood pressure .007; 1.44; 1.10, 1.87) be significantly independently associated Conclusion: This provides first free-living, elderly black Americans. 6.8% cohort. showed no ethnicity. However, low levels, pressure. (J Vasc Surg 2002;36:443-51.)