Regulation of pantothenate kinase by coenzyme A and its thioesters.

作者: D.S. Vallari , S. Jackowski , C.O. Rock

DOI: 10.1016/S0021-9258(18)61527-3

关键词: PhosphorylationBiosynthesisCarbohydrate metabolismPantothenate kinaseBiochemistryCoenzyme APantothenate kinase activityBiologyThioesterEnzyme

摘要: … CoA act coordinately to regulate CoA biosynthesis. We calculate from the kinetic constants for pantothenate … in this study together with the intracellular levels of CoA (5, 6) (Table 11) and …

参考文章(29)
J R Neely, M N Fisher, J D Robishaw, The properties and regulation of pantothenate kinase from rat heart. Journal of Biological Chemistry. ,vol. 260, pp. 15745- 15751 ,(1985) , 10.1016/S0021-9258(17)36321-4
Henry J. Vogel, David M. Bonner, Acetylornithinase of Escherichia coli: partial purification and some properties. Journal of Biological Chemistry. ,vol. 218, pp. 97- 106 ,(1956) , 10.1016/S0021-9258(18)65874-0
O.H. Lowry, J. Carter, J.B. Ward, Luis Glaser, The Effect of Carbon and Nitrogen Sources on the Level of Metabolic Intermediates in Escherichia coli Journal of Biological Chemistry. ,vol. 246, pp. 6511- 6521 ,(1971) , 10.1016/S0021-9258(19)34144-4
Tadahiko KARASAWA, Kouichi YOSHIDA, Kiyoshi FURUKAWA, Kanoo HOSOKI, Feedback inhibition of pantothenate kinase by coenzyme A and possible role of the enzyme for the regulation of cellular coenzyme A level. Journal of Biochemistry. ,vol. 71, pp. 1065- 1067 ,(1972) , 10.1093/OXFORDJOURNALS.JBCHEM.A129854
G.B. Stokes, P.K. Stumpf, Fat metabolism in higher plants Archives of Biochemistry and Biophysics. ,vol. 162, pp. 638- 648 ,(1974) , 10.1016/0003-9861(74)90226-4
Gary L. Powell, John Elovson, P. Roy Vagelos, Acyl carrier protein. XII. Synthesis and turnover of the prosthetic group of acyl carrier protein in vivo. Journal of Biological Chemistry. ,vol. 244, pp. 5616- 5624 ,(1969) , 10.1016/S0021-9258(18)63605-1
S Jackowski, C O Rock, Turnover of the 4'-phosphopantetheine prosthetic group of acyl carrier protein. Journal of Biological Chemistry. ,vol. 259, pp. 1891- 1895 ,(1984) , 10.1016/S0021-9258(17)43491-0
E E Snell, S G Powers, Ketopantoate hydroxymethyltransferase. II. Physical, catalytic, and regulatory properties. Journal of Biological Chemistry. ,vol. 251, pp. 3786- 3793 ,(1976) , 10.1016/S0021-9258(17)33413-0