Linked Genes, Pseudoalleles and Blood Groups

作者: Clyde Stormont

DOI: 10.1086/281869

关键词: GeneticsGenetic linkageConfusionRh blood group systemBiologyAntigenGeneMultiple alleles

摘要: The theory of closely or absolutely linked genes and "pseudoallelic" genic elements as applied to blood groups is critically examined both at the level antigen gene. most complex system recognized date in any species, namely "B" cattle, used a model throughout discussion. Comparisons are drawn between certain features B Rh man regard kind explanation involved "CDE" symbolism groups. At outset it pointed out that notion and/or pseudoalleles traces erroneous impression single specificity definitive characteristic an antigen. Hence, has constituted problem study only insofar led confusion interpreting serological results. hypothesis multiple alleles proposed explain more systems still exist can be mainta...

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