Enzymic regulation of procyanidin biosynthesis; lack of a flav-3-en-3-ol intermediate
作者： Helen A. Stafford
DOI: 10.1016/S0031-9422(00)97664-7
关键词: Multienzyme complexes 、 Biosynthesis 、 Chemistry 、 Proanthocyanidin 、 Stereochemistry 、 Tannin 、 Condensing enzyme 、 Condensed tannin
摘要: Abstract A speculative scheme for procyanidin (condensed tannin) biosynthesis involving multienzyme complexes is presented in which the stereochemistry at C-3 and C-4 of (+)-dihydroquercetin maintained (+)-catechin its oligomeric products. This contrast to Haslam's speculation a symmetrical flav-3-en-3-ol intermediate, requires re-introduction terminal reduction steps. In proposed scheme, origin 2,3- cis (−)-epicatechin from would require an epimerase, addition two reductases condensing enzyme neeeded stereochemistry.
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