Primary mediastinal non-Hodgkin's lymphomas: a morphologic and immunologic study of 19 cases.

摘要: Nineteen, primary, non-lymphoblastic, non-Hodgkin’s lymphomas were investigated by conventional morphologic studies as well immunologic using the application of a battery monoclonal antibodies to frozen tissue sections. Seventeen diffuse large cell; one was cell immunoblastic and follicular lymphoma intermediate differentiation. Thirty-seven percent showed prominent sclerosis, sometimes associated with superior vena cava syndrome. Six cases evidence immunoglobulin production light chain restriction. Twelve additional shown be B-cell lineage B1/T015 expression but did not show production. One case T-cell helper phenotype. Ia found in 14 18 studied.