Tetracationic fluorinated zinc(ii)phthalocyanine: Synthesis, characterization and DNA-binding properties
作者： Mukaddes Özçeşmeci , Özgür Bülent Ecevit , Serdar Sürgün , Esin Hamuryudan
DOI: 10.1016/J.DYEPIG.2012.06.018
关键词: Fluorine-19 NMR 、 Phthalonitrile 、 Zinc 、 Methyl iodide 、 Proton NMR 、 Derivative (chemistry) 、 Phthalocyanine 、 Fluorescence spectroscopy 、 Chemistry 、 Photochemistry 、 Polymer chemistry
摘要: Abstract Selective replacement of the p-fluorine atom 4-(2′,3′,4′,5′,6′-pentafluorobenzyloxy) phthalonitrile with N,N-dimethylaminoetanethiol gave 4-[2′,3′,5′,6′-tetrafluoro-4′-(2-dimethylaminoetanethio)benzyloxy]phthalonitrile. A peripherally tetra-substituted zinc(II) phthalocyanine was achieved by tetramerization new perfluorobenzyloxyphthalonitrile in presence zinc acetate. The derivative quaternized methyl iodide to afford a water-soluble product. compounds were characterized using elemental analyses, 1H NMR, 19F UV–vis and FT-IR spectroscopy mass spectrometry. interaction between calf thymus DNA investigated tris buffer (pH 7.4) absorption fluorescence spectroscopy. Upon addition phthalocyanine, change thermal denaturation profile observed.
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