Descriptive epidemiology of cancers of the upper respiratory tract in los angeles

摘要: The descriptive epidemiology of cancer three upper respiratory tract sites (lip; mouth and pharynx, excluding nasopharynx; nose, sinus nasopharynx) was explored using data from 1972–1976 the population-based registry covering Los Angeles County, California. In addition, proportion cases at each site which are explained by tobacco use estimated attributable risks calculated previously published case-control studies. Causes nontobaccorelated considered. Lip found to be a disease predominantly white males with male/female ratio 9.8 for lower lip 1.0 lip. Tobacco is responsible 60% male cancers, incidence rates after subtraction due were more than times greater in men women. A hypothesis proposed that an important etiologic factor exposure sun, wind cold results chapping; this most intense lip; coverings women protects their lips both sun chapping. Cigarette smoking 51% pharynx smoking, similar. Factors such as poor dentition nutritional deficiencies may help explain demographic characteristics higher among social classes secular decline rates. Cancers nasopharynx occur workers wide range occupations industries involved inhalation dust, fumes vapors. High observed Chinese high Spanish-surnamed residents. these appear related action carcinogens on tissue chronically irritated repeated infections or allergic responses. addition racial differences physical structure nasal passage influence where inhaled particles deposited. Cancer 49:2201–2207, 1982.