Depression in patients referred to a dementia clinic. A three-year prospective study

摘要: Of 225 patients referred to a dementia clinic, depression occurred in 31 (70%) of 44 not thought be demented, six (24%) 25 with cognitive impairment severe enough warrant the label dementia, and 24 (15%) 156 various forms including 19 (19%) 99 Alzheimer-type dementia. Follow-up over three years has shown that 16 (57%) 28 depressed, nondemented went on develop frank Thirteen these had some sign, often subtle, organic neurologic disease. Depressed elderly any following are at high risk dementia: evidence cerebrovascular, extrapyramidal, or spinocerebellar disease; modified Hachinski ischemic score 4 greater; Mental Status Questionnaire under 8; behavior 7 higher; confusion low doses tricyclic antidepressants. Dementing illnesses can present as relatively little impairment.