Herpes Simplex Virus Meningoencephalitis

摘要: Herpes simplex virus types 1 and 2 (HSV-1 2) are human neutropic viruses that establish latent infection in dorsal root ganglia for the entire life of host. From this reservoir they can reactivate to cause morbidity mortality. encephalitis (HSE) is one most devastating disorders caused by these viruses. The biology their ability latency, maintain it host, reactivate, primary recurrent disease being studied animal models humans. Of special interest question whether HSE result or outcome reactivation? present review covers biological, medical, neurological aspects HSE, focusing on recent molecular findings gene expression during HSV-1. Despite accumulating knowledge, there still several issues regarding both pathogenesis therapy HSV-1 currently defy understanding.