Diffusion-weighted MRI in early assessment of tumour response to radiotherapy in high-risk prostate cancer
作者： L Liu , N Wu , H Ouyang , JR Dai , WH Wang
DOI: 10.1259/BJR.20140359
关键词: Retrospective cohort study 、 Effective diffusion coefficient 、 Clinical recurrence 、 Diffusion MRI 、 Prostate cancer 、 Radiation therapy 、 Tumour response 、 Nuclear medicine 、 Follow up studies 、 Medicine
摘要: Objective:The objective of this study was to assess the efficacy diffusion-weighted MRI (DWI) in monitoring response radiotherapy high-risk prostate cancer (PC).Methods:This retrospective included 78 patients with PC undergoing 3.0-T (supplemented by DWI) before and after intensity-modulated (IMRT). Based on follow-up clinical examinations, were divided into two groups: recurrence group (patients who suffered biochemical/clinical within 3 years, n = 13) non-recurrence free for over n = 65). The apparent diffusion coefficient (ADC) values IMRT compared between these groups. receiver-operating characteristics (ROC) analysis carried out investigate discriminatory capability pre- post-IMRT ADC values.Results:The overall 1.04 ± 0.18 × 10−3 mm2 s−1 PCs 1.45 ± 0.15 × 10−3 mm2 s−1 (p < 0.001). A statis...
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