Blood stream infections (BSI) in severe burn patients—Early and late BSI: A 9-year study

作者: Ayelet Raz-Pasteur , Khetam Hussein , Renato Finkelstein , Yehuda Ullmann , Dana Egozi

DOI: 10.1016/J.BURNS.2012.09.015

关键词: Severe burnPediatricsRetrospective cohort studyYoung adultSepsisIncidence (epidemiology)BacteremiaBlood streamPseudomonas aeruginosaMedicine

摘要: Bloodstream infections (BSI) and sepsis are among the most common complications occurring in severe burn patients. This study was designed to evaluate changes BSI pathogens over almost a decade patients at Rambam Healthcare Campus, occurrence during early late hospitalization periods. Retrospective computerized data retrieved from all hospitalized our institution years 2001-2009. first week defined as BSI, second beyond, BSI. Of 159 burns patients, 74 had least one episode. Most episodes were diagnosed of hospitalization. In an increased prevalence resistant bacteria (methicillin-resistant Staphylococcus aureus [MRSA], carbapenem-resistant Klebsiella pneumoniae [CRKP], imipenem-resistant Pseudomonas aeruginosa [PSE-IMP]) Candida spp. observed. However, 9-year period, only CRKP significantly. summary, except for sudden appearance increase (8% increase; p=0.045), we did not observe significant change pathogen profile period. Nevertheless, there is clear profile, especially after 4 weeks

参考文章(29)
Mark Ansermino, Carolyn Hemsley, Intensive care management and control of infection BMJ. ,vol. 329, pp. 220- 223 ,(2004) , 10.1136/BMJ.329.7459.220
Erika Bruck, National Committee for Clinical Laboratory Standards. Pediatrics. ,vol. 65, pp. 187- 188 ,(1980)
Po-Ren Hsueh, Lee-Jene Teng, Pan-Chyr Yang, Yu-Chi Chen, Shen-Wu Ho, Kwen-Tay Luh, Persistence of a multidrug-resistant Pseudomonas aeruginosa clone in an intensive care burn unit. Journal of Clinical Microbiology. ,vol. 36, pp. 1347- 1351 ,(1998) , 10.1128/JCM.36.5.1347-1351.1998
Joel N. Maslow, Thomas Glaze, Pamela Adams, Max Lataillade, Concurrent outbreak of multidrug-resistant and susceptible subclones of Acinetobacter baumannii affecting different wards of a single hospital. Infection Control and Hospital Epidemiology. ,vol. 26, pp. 69- 75 ,(2005) , 10.1086/502489
Helio S. Sader, David J. Farrell, Ronald N. Jones, Antimicrobial susceptibility of Gram-positive cocci isolated from skin and skin-structure infections in European medical centres. International Journal of Antimicrobial Agents. ,vol. 36, pp. 28- 32 ,(2010) , 10.1016/J.IJANTIMICAG.2010.03.016
Rameshwar L. Bang, Raj K. Gang, Suhas C. Sanyal, Eiman Mokaddas, Mohammed K. Ebrahim, Burn septicaemia: an analysis of 79 patients. Burns. ,vol. 24, pp. 354- 361 ,(1998) , 10.1016/S0305-4179(98)00022-9
David A. Dean, Kenneth W. Burchard, Fungal infection in surgical patients American Journal of Surgery. ,vol. 171, pp. 374- 382 ,(1996) , 10.1016/S0002-9610(97)89647-X
John Fitzwater, Gary F. Purdue, John L. Hunt, Grant E. O???Keefe, The risk factors and time course of sepsis and organ dysfunction after burn trauma. Journal of Trauma-injury Infection and Critical Care. ,vol. 54, pp. 959- 966 ,(2003) , 10.1097/01.TA.0000029382.26295.AB
Robert P Rennie, Ronald N Jones, Alan H Mutnick, SENTRY Program Study Group, Occurrence and antimicrobial susceptibility patterns of pathogens isolated from skin and soft tissue infections: report from the SENTRY Antimicrobial Surveillance Program (United States and Canada, 2000). Diagnostic Microbiology and Infectious Disease. ,vol. 45, pp. 287- 293 ,(2003) , 10.1016/S0732-8893(02)00543-6
Ulku Altoparlak, Serpil Erol, Mufide N. Akcay, Fehmi Celebi, Ayten Kadanali, The time-related changes of antimicrobial resistance patterns and predominant bacterial profiles of burn wounds and body flora of burned patients Burns. ,vol. 30, pp. 660- 664 ,(2004) , 10.1016/J.BURNS.2004.03.005