Biologic response of B lymphoma cells to anti-CD20 monoclonal antibody rituximab in vitro: CD55 and CD59 regulate complement-mediated cell lysis

作者: Josée Golay , Luisella Zaffaroni , Thomas Vaccari , Manuela Lazzari , Gian-Maria Borleri

DOI: 10.1182/BLOOD.V95.12.3900

关键词: AntibodyCancer researchLymphomaCytotoxicityRituximabAntibody-dependent cell-mediated cytotoxicityAntigenImmunologyMonoclonalBiologyCD59

摘要: … in fresh cases of FL: Blocking CD55 and/or CD59 function with … Furthermore, we suggest that the relative levels of CD55 and … not inhibit proliferation or induce significant apoptosis in any …

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