A comprehensive review of lysine-specific demethylase 1 and its roles in cancer.

作者: Amir Hosseini , Saverio Minucci

DOI: 10.2217/EPI-2017-0022

关键词: DemethylaseHistone DemethylasesBiologyHistone codeCell biologyHistone methyltransferaseCancer epigeneticsBiochemistryHistone methylationKDM1AEZH2

摘要: … Lysine-specific demethylase 1(LSD1, also known as KDM1A) is the first discovered histone lysine demethylase, with the ability to demethylase H3K4me1/2 and H3K9me1/2 at target …

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