Syndrome of multiple bowel perforations in liver transplant recipients.

摘要: In an analysis of surgical complications following 500 consecutive orthotopic liver transplants, we identified 12 patients who developed the syndrome multiple bowel perforations that was not due to iatrogenic injury. All cases occurred in small children (mean weight: 9.0 kg), represented 7% pediatric population. Each patient had a minimum three perforations. The typical intraoperative findings were pin-point areas normal-appearing bowel. With only one possible exception (a with cytomegalovirus enteritis), no specific etiology could be determined. Management based on exploratory laparotomies and individualized operative procedures. are currently alive follow-up: 34.9 months). pathogenesis remains unclear but is possibly multifactorial or related high doses steroids. Aggressive management semiopen treatment peritonitis frequent explorations has afforded excellent results.